
For managing constipation that is one of the most frequent side effects your doctor may recommend taking greater fluids, taking in more of fiber, or using a stool softener or a laxative.
Avoid Alcohol and Certain Medications
Combining opioids and alcohol and other sedatives, such as benzodiazepines (e.g., Xanax, Valium) may be dangerous. Combining them could cause breathing to slow down to the point which is dangerous. Make sure to talk with your doctor or pharmacist prior to mixing other drugs with opioids, including over-the-counter medications or supplements.