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Tramadol hydrochloride is a synthetic opioid analgesic that works centrally to relieve moderate to severe pain. It acts by attaching to mu-opioid receptors in the central nervous system and reducing serotonin and norepinephrine reuptake, which helps to regulate pain perception. It works similarly to codeine but is thought to have a lower potential for misuse when compared to other opioids.
Tramadol comes in several forms, including immediate-release tablets, extended-release tablets, and capsules. The average starting dose for adults is 25 mg to 50 mg every four to six hours, as needed for pain relief. Adults should not exceed a daily intake of 400 mg.
