Ultram is fast and almost entirely absorbed after intramuscular administration. A maximum of 0.75 hours and a Cmax of 166 g/L were found after administering 50 mg of Ultram.
A high of 294 g/L and a maximum of 3.3 hours were found after rectal administration of 100 mg Ultram suppositories. Absolute bioavailability was shown to be higher (77% vs. 75%) following rectal delivery because oral administration has a higher first-pass metabolism. You can always buy Ultram online.
